McFall-Ngai Lab: Publications
- Truong TV, Holland DB, Madaan S, Andreev A, Keomanee-Dizon K, Troll JV, Koo DES, McFall-Ngai MJ, Fraser SE. Author Correction: High-contrast, synchronous volumetric imaging with selective volume illumination microscopy. Communications biology 2022. 5((1)),363
- Lynch JB, James N, McFall-Ngai M, Ruby EG, Shin S, Takagi D. Transitioning to confined spaces impacts bacterial swimming and escape response. Biophysical journal 2022.
- Nyholm SV, McFall-Ngai MJ. Publisher Correction: A lasting symbiosis: how the Hawaiian bobtail squid finds and keeps its bioluminescent bacterial partner. Nature reviews. Microbiology 2022. 20((5)),315
- Bongrand C, Koch E, Mende D, Romano A, Lawhorn S, McFall-Ngai M, DeLong EF, Ruby EG. Evidence of Genomic Diversification in a Natural Symbiotic Population Within Its Host. Frontiers in microbiology 2022. 13854355
- McFall-Ngai M. Building a career during a revolution in biology. Nature microbiology 2022. 7((3)),347-348
- McFall-Ngai M, Ruby E. Getting the Message Out: the Many Modes of Host-Symbiont Communication during Early-Stage Establishment of the Squid-Vibrio Partnership. mSystems 2021. 6((5)),e0086721
- Essock-Burns T, Bennett BD, Arencibia D, Moriano-Gutierrez S, Medeiros M, McFall-Ngai MJ, Ruby EG. Bacterial Quorum-Sensing Regulation Induces Morphological Change in a Key Host Tissue during the Euprymna scolopes-Vibrio fischeri Symbiosis. mBio 2021. 12((5)),e0240221
- McFall-Ngai M. Keeping the clock running: The microbiome as a pivotal timekeeper. Cell metabolism 2021. 33((8)),1514-1515
- Nyholm SV, McFall-Ngai MJ. A lasting symbiosis: how the Hawaiian bobtail squid finds and keeps its bioluminescent bacterial partner. Nature reviews. Microbiology 2021. 19((10)),666-679
- Moriano-Gutierrez S, Ruby EG, McFall-Ngai MJ. MicroRNA-Mediated Regulation of Initial Host Responses in a Symbiotic Organ. mSystems 2021. 6((3)),
- Bosch TCG, McFall-Ngai M. Animal development in the microbial world: Re-thinking the conceptual framework. Current topics in developmental biology 2021. 141399-427
- McFall-Ngai M, Bosch TCG. Animal development in the microbial world: The power of experimental model systems. Current topics in developmental biology 2021. 141371-397
- Finlay BB, Amato KR, Azad M, Blaser MJ, Bosch TCG, Chu H, Dominguez-Bello MG, Ehrlich SD, Elinav E, Geva-Zatorsky N, Gros P, Guillemin K, Keck F, Korem T, McFall-Ngai MJ, Melby MK, Nichter M, Pettersson S, Poinar H, Rees T, Tropini C, Zhao L, Giles-Vernick T. The hygiene hypothesis, the COVID pandemic, and consequences for the human microbiome. Proceedings of the National Academy of Sciences of the United States of America 2021. 118((6)),
- Moriano-Gutierrez S, Bongrand C, Essock-Burns T, Wu L, McFall-Ngai MJ, Ruby EG. The noncoding small RNA SsrA is released by Vibrio fischeri and modulates critical host responses. PLoS biology 2020. 18((11)),e3000934
- Aschtgen MS, Brennan CA, Nikolakakis K, Cohen S, McFall-Ngai M, Ruby EG. Insights into flagellar function and mechanism from the squid-vibrio symbiosis. NPJ biofilms and microbiomes 2020. 5((1)),32
- Koch EJ, Bongrand C, Bennett BD, Lawhorn S, Moriano-Gutierrez S, Pende M, Vadiwala K, Dodt HU, Raible F, Goldman W, Ruby EG, McFall-Ngai M. The cytokine MIF controls daily rhythms of symbiont nutrition in an animal-bacterial association. Proceedings of the National Academy of Sciences of the United States of America 2020. 117((44)),27578-27586
- Koch EJ, Moriano-Gutierrez S, Ruby EG, McFall-Ngai M, Liebeke M. The impact of persistent colonization by on the metabolome of the host squid . The Journal of experimental biology 2020. 223((Pt 16)),
- Essock-Burns T, Bongrand C, Goldman WE, Ruby EG, McFall-Ngai MJ. Interactions of Symbiotic Partners Drive the Development of a Complex Biogeography in the Squid-Vibrio Symbiosis. mBio 2020. 11((3)),
- Cohen SK, Aschtgen MS, Lynch JB, Koehler S, Chen F, Escrig S, Daraspe J, Ruby EG, Meibom A, McFall-Ngai M. Tracking the cargo of extracellular symbionts into host tissues with correlated electron microscopy and nanoscale secondary ion mass spectrometry imaging. Cellular microbiology 2020. 22((4)),e13177
- Bongrand C, Moriano-Gutierrez S, Arevalo P, McFall-Ngai M, Visick KL, Polz M, Ruby EG. Using Colonization Assays and Comparative Genomics To Discover Symbiosis Behaviors and Factors in Vibrio fischeri. mBio 2020. 11((2)),
- Truong TV, Holland DB, Madaan S, Andreev A, Keomanee-Dizon K, Troll JV, Koo DES, McFall-Ngai MJ, Fraser SE. High-contrast, synchronous volumetric imaging with selective volume illumination microscopy. Communications biology 2020. 3((1)),74
- Koch EJ, Moriano-Gutierrez S, Ruby EG, McFall-Ngai M, Liebeke M. The impact of persistent colonization by Vibrio fischeri on the metabolome of the host squid Euprymna scolopes. The Journal of experimental biology 2020.
- Martiny JBH, Whiteson KL, Bohannan BJM, David LA, Hynson NA, McFall-Ngai M, Rawls JF, Schmidt TM, Abdo Z, Blaser MJ, Bordenstein S, Bréchot C, Bull CT, Dorrestein P, Eisen JA, Garcia-Pichel F, Gilbert J, Hofmockel KS, Holtz ML, Knight R, Mark Welch DB, McDonald D, Methé B, Mouncey NJ, Mueller NT, Pfister CA, Proctor L, Sachs JL. The emergence of microbiome centres. Nature microbiology 2019. 5((1)),2-3
- Aschtgen MS, Brennan CA, Nikolakakis K, Cohen S, McFall-Ngai M, Ruby EG. Insights into flagellar function and mechanism from the squid-vibrio symbiosis. NPJ biofilms and microbiomes 2019. 5((1)),32
- Gruber-Vodicka HR, Leisch N, Kleiner M, Hinzke T, Liebeke M, McFall-Ngai M, Hadfield MG, Dubilier N. Two intracellular and cell type-specific bacterial symbionts in the placozoan Trichoplax H2. Nature microbiology 2019. 4((9)),1465-1474
- Bosch TCG, Guillemin K, McFall-Ngai M. Evolutionary "Experiments" in Symbiosis: The Study of Model Animals Provides Insights into the Mechanisms Underlying the Diversity of Host-Microbe Interactions. BioEssays : news and reviews in molecular, cellular and developmental biology 2019. 41((10)),e1800256
- Moriano-Gutierrez S, Koch EJ, Bussan H, Romano K, Belcaid M, Rey FE, Ruby EG, McFall-Ngai MJ. Critical symbiont signals drive both local and systemic changes in diel and developmental host gene expression. Proceedings of the National Academy of Sciences of the United States of America 2019. 116((16)),7990-7999
- Belcaid M, Casaburi G, McAnulty SJ, Schmidbaur H, Suria AM, Moriano-Gutierrez S, Pankey MS, Oakley TH, Kremer N, Koch EJ, Collins AJ, Nguyen H, Lek S, Goncharenko-Foster I, Minx P, Sodergren E, Weinstock G, Rokhsar DS, McFall-Ngai M, Simakov O, Foster JS, Nyholm SV. Symbiotic organs shaped by distinct modes of genome evolution in cephalopods. Proceedings of the National Academy of Sciences of the United States of America 2019. 116((8)),3030-3035
- Kremer N, Koch EJ, El Filali A, Zhou L, Heath-Heckman EAC, Ruby EG, McFall-Ngai MJ. Persistent Interactions with Bacterial Symbionts Direct Mature-Host Cell Morphology and Gene Expression in the Squid-Vibrio Symbiosis. mSystems 2018. 3((5)),e00165-18
- Peyer, SM, N Kremer, M McFall-Ngai. Involvement of a host cathepsin L in symbiont-induced cell death Microbiology Open 2018. 7(5),
- Truong, TV, DB Holland, S Madaan, A Andreev, JV Troll, DES Koo, K Keomanee-Dizo, MJ McFall-Ngai, SE Frazer. Selective volume illumination microscopy offers synchronous volumetric imaging with high contrast. bioRxiv 2018. 0(0),0
- Koehler S, Gaedeke R, Thompson C, Bongrand C, Visick KL, Ruby E, McFall-Ngai M. The model squid-vibrio symbiosis provides a window into the impact of strain- and species-level differences during the initial stages of symbiont engagement. Environmental microbiology 2018.
- Koch EJ, McFall-Ngai M. Model systems for the study of how symbiotic associations between animals and extracellular bacterial partners are established and maintained. Drug discovery today. Disease models 2018. 283-12
- Peyer SM, Kremer N, McFall-Ngai MJ. Involvement of a host Cathepsin L in symbiont-induced cell death. MicrobiologyOpen 2018. 7((5)),e00632
- Nawroth JC, Guo H, Koch E, Heath-Heckman EAC, Hermanson JC, Ruby EG, Dabiri JO, Kanso E, McFall-Ngai M. Motile cilia create fluid-mechanical microhabitats for the active recruitment of the host microbiome. Proceedings of the National Academy of Sciences of the United States of America 2017. 114((36)),9510-9516
- Rook G, Bäckhed F, Levin BR, McFall-Ngai MJ, McLean AR. Evolution, human-microbe interactions, and life history plasticity. Lancet (London, England) 2017. 390((10093)),521-530
- Chen F, Krasity BC, Peyer SM, Koehler S, Ruby EG, Zhang X, McFall-Ngai MJ. Bactericidal Permeability-Increasing Proteins Shape Host-Microbe Interactions. mBio 2017. 8((2)),
- Peyer SM, Heath-Heckman EAC, McFall-Ngai MJ. Characterization of the cell polarity gene crumbs during the early development and maintenance of the squid-vibrio light organ symbiosis. Development genes and evolution 2017. 227((6)),375-387
- Casadevall A, Ellis LM, Davies EW, McFall-Ngai M, Fang FC. Reply to "Improving Microbiology Research: the Problems Are Less Statistical and More Biological". mBio 2016. 7((5)),
- Heath-Heckman EA, Foster J, Apicella MA, Goldman WE, McFall-Ngai M. Environmental cues and symbiont microbe-associated molecular patterns function in concert to drive the daily remodelling of the crypt-cell brush border of the Euprymna scolopes light organ. Cellular microbiology 2016. 18((11)),1642-1652
- Casadevall A, Ellis LM, Davies EW, McFall-Ngai M, Fang FC. A Framework for Improving the Quality of Research in the Biological Sciences mBio 2016. 7(4),e01256-16
- Alivisatos AP, Blaser MJ, Brodie EL, Chun M, Dangl JL, Donohue TJ, Dorrestein PC, Gilbert JA, Green JL, Jansson JK, Knight R, Maxon ME, McFall-Ngai MJ, Miller JF, Pollard KS, Ruby EG, Taha SA, . MICROBIOME. A unified initiative to harness Earth's microbiomes. Science (New York, N.Y.) 2015. 350((6260)),507-8
- Nikolakakis K, Lehner EM, McFall-Ngai MJ, Ruby EG. Use of hybridization chain reaction-fluorescent in situ hybridization (HCR-FISH) to track gene expression by both partners during initiation of symbiosis. Appl Environ Microbiol 2015. 81(14),4728-4735
- Schwartzman JA, Koch E, Heath-Heckman EAC, Zhou L, Kremer N, McFall-Ngai MJ, Ruby EG. The chemistry of negotiation: rhythmic, glycan-driven acidification in a symbiotic conversation. Proc Natl Acad Sci USA 2015. 112(2),566-571
- McFall-Ngai MJ. The importance of microbes in animal development: lessons from the squid-vibrio symbiosis. Annu. Rev. Microbiol. 2014. 68177-94
- Kremer N, Schwartzman J, Augustin R, Zhou L, Ruby EG, Hourdez S, McFall-Ngai MJ. The dual nature of haemocyanin in the establishment and persistence of the squid-vibrio symbiosis. Proc. Biol. Sci. 2014. 281(1785),20140504
- Heath-Heckman EA, Gillette AA, Augustin R, Gillette MX, Goldman WE, McFall-Ngai MJ. Shaping the microenvironment: evidence for the influence of a host galaxin on symbiont acquisition and maintenance in the squid-vibrio symbiosis. Environ. Microbiol. 2014.
- Koch EJ, Miyashiro T, McFall-Ngai MJ, Ruby EG. Features governing symbiont persistence in the squid-vibrio association. Mol. Ecol. 2014. 23(6),1624-34
- Brennan CA, Hunt JR, Kremer N, Krasity BC, Apicella MA, McFall-Ngai MJ, Ruby EG. A model symbiosis reveals a role for sheathed-flagellum rotation in the release of immunogenic lipopolysaccharide. Elife 2014. 3e01579
McFall-Ngai MJ. Divining the Essence of Symbiosis: Insights from the Squid-Vibrio Model PLOS Biol. 2014. 12(2),
Koropatnick T, Goodson MS, Heath-Heckman EAC, McFall-Ngai MJ. Identifying the Cellular Mechanisms of Symbiont-Induced Epithelial Morphogenesis in the Squid-Vibrio Association Biol. Bull. 2014. 226(1),56-68
Peyer SM, Pankey MS, Oakley TH, McFall-Ngai MJ. Eye-specification genes in the bacterial light organ of the bobtail squid Euprymna scolopes, and their expression in response to symbiont cues. Mech. Dev. 2014. 131111-26
- Nyholm SV, McFall-Ngai MJ. Animal development in a microbial world. 2014.
Kremer N, Philipp EE, Carpentier MC, Brennan CA, Kraemer L, Altura MA, Augustin R, Häsler R, Heath-Heckman EA, Peyer SM, Schwartzman J, Rader BA, Ruby EG, Rosenstiel P, McFall-Ngai MJ. Initial symbiont contact orchestrates host-organ-wide transcriptional changes that prime tissue colonization. Cell Host Microbe 2013. 14(2),183-94
- Altura MA, Heath-Heckman EA, Gillette A, Kremer N, Krachler AM, Brennan C, Ruby EG, Orth K, McFall-Ngai MJ. The first engagement of partners in the Euprymna scolopes-Vibrio fischeri symbiosis is a two-step process initiated by a few environmental symbiont cells. Environ. Microbiol. 2013.
- Heath-Heckman EA, Peyer SM, Whistler CA, Apicella MA, Goldman WE, McFall-Ngai MJ. Bacterial bioluminescence regulates expression of a host cryptochrome gene in the squid-Vibrio symbiosis. MBio 2013. 4(2),
- McFall-Ngai M, Hadfield MG, Bosch TC, Carey HV, Domazet-Loso T, Douglas AE, Dubilier N, Eberl G, Fukami T, Gilbert SF, Hentschel U, King N, Kjelleberg S, Knoll AH, Kremer N, Mazmanian SK, Metcalf JL, Nealson K, Pierce NE, Rawls JF, Reid A, Ruby EG, Rumpho M, Sanders JG, Tautz D, Wernegreen JJ. Animals in a bacterial world, a new imperative for the life sciences. Proc. Natl. Acad. Sci. U.S.A. 2013. 110(9),3229-36
Hentschel U, Weis VM, McFall-Ngai MJ. Biological bulletin virtual symposium: discoveries in animal symbiosis in the “omics” age. Biol. Bull. 2012. 223(1),5-6
- Mandel MJ, Schaefer AL, Brennan CA, Heath-Heckman EA, Deloney-Marino CR, McFall-Ngai MJ, Ruby EG. Squid-derived chitin oligosaccharides are a chemotactic signal during colonization by Vibrio fischeri. Appl. Environ. Microbiol. 2012. 78(13),4620-6
- Rader BA, Kremer N, Apicella MA, Goldman WE, McFall-Ngai MJ. Modulation of symbiont lipid A signaling by host alkaline phosphatases in the squid-vibrio symbiosis. MBio 2012. 3(3),
- Post DM, Yu L, Krasity BC, Choudhury B, Mandel MJ, Brennan CA, Ruby EG, McFall-Ngai MJ, Gibson BW, Apicella MA. O-antigen and core carbohydrate of Vibrio fischeri lipopolysaccharide: composition and analysis of their role in Euprymna scolopes light organ colonization. J. Biol. Chem. 2012. 287(11),8515-30
- McFall-Ngai, MJ, Heath-Heckman EA, Gilette AA, Peyer SM, Harvie EA. The secret languages of coevolved symbioses: insights from the Euprymna scolopes-Vibrio fischeri symbiosis. Semin. Immunol. 2012. 243-8
- McFall-Ngai MJ, Ruby EG. Deciphering the language of diplomacy: give and take in the study of the squid-vibrio symbiosis. 2012. 173-80
Bosch TC, McFall-Ngai MJ. Metaorganisms as the new frontier. Zoology (Jena) 2011. 114(4),185-90
- Heath-Heckman EA, McFall-Ngai MJ. The occurrence of chitin in the hemocytes of invertebrates. Zoology (Jena) 2011. 114(4),191-8
Krasity BC, Troll JV, Weiss JP, McFall-Ngai MJ. LBP/BPI proteins and their relatives: conservation over evolution and roles in mutualism. Biochem. Soc. Trans. 2011. 39(4),1039-44
- Phillips NJ, Adin DM, Stabb EV, McFall-Ngai MJ, Apicella MA, Gibson BW. The lipid A from Vibrio fischeri lipopolysaccharide: a unique structure bearing a phosphoglycerol moiety. J. Biol. Chem. 2011. 286(24),21203-19
- Altura MA, Stabb E, Goldman W, Apicella M, McFall-Ngai MJ. Attenuation of host NO production by MAMPs potentiates development of the host in the squid-vibrio symbiosis. Cell. Microbiol. 2011. 13(4),527-37
- Wang Y, Dunn AK, Wilneff J, McFall-Ngai MJ, Spiro S, Ruby EG. Vibrio fischeri flavohaemoglobin protects against nitric oxide during initiation of the squid-Vibrio symbiosis. Mol. Microbiol. 2010. 78(4),903-15
Troll JV, Bent EH, Pacquette N, Wier AM, Goldman WE, Silverman N, McFall-Ngai MJ. Taming the symbiont for coexistence: a host PGRP neutralizes a bacterial symbiont toxin. Environ. Microbiol. 2010. 12(8),2190-203
- McFall-Ngai, MJ, Nyholm SV, Castillo MG. The role of the immune system in the initiation and persistence of the Euprymna scolopes--Vibrio fischeri symbiosis. Semin. Immunol. 2010. 22(1),48-53
- Wier AM, Nyholm SV, Mandel MJ, Massengo-Tiassé RP, Schaefer AL, Koroleva I, Splinter-Bondurant S, Brown B, Manzella L, Snir E, Almabrazi H, Scheetz TE, Bonaldo Mde F, Casavant TL, Soares MB, Cronan JE, Reed JL, Ruby EG, McFall-Ngai MJ. Transcriptional patterns in both host and bacterium underlie a daily rhythm of anatomical and metabolic change in a beneficial symbiosis. Proc. Natl. Acad. Sci. U.S.A. 2010. 107(5),2259-64
- Lee PN, McFall-Ngai MJ, Callaerts P, de Couet HG. The Embryonic Development of the Hawaiian bobtail squid (Euprymna scolopes). Cold Spring Harb Protoc 2009. 2009(11),pdb.ip77
- Lee PN, McFall-Ngai MJ, Callaerts P, de Couet HG. Whole-mount in situ hybridization of Hawaiian bobtail squid (Euprymna scolopes) embryos with DIG-labeled riboprobes: II. Embryo preparation, hybridization, washes, and immunohistochemistry. Cold Spring Harb Protoc 2009. 2009(11),pdb.prot5322
- Lee PN, McFall-Ngai MJ, Callaerts P, de Couet HG. Whole-mount in situ hybridization of Hawaiian bobtail squid (Euprymna scolopes) embryos with DIG-labeled riboprobes: I. DNA template preparation and in vitro transcription of riboprobes. Cold Spring Harb Protoc 2009. 2009(11),pdb.prot5321
- Lee PN, McFall-Ngai MJ, Callaerts P, de Couet HG. Confocal immunocytochemistry of embryonic and juvenile Hawaiian bobtail squid (Euprymna scolopes) tissues. Cold Spring Harb Protoc 2009. 2009(11),pdb.prot5320
- Lee PN, McFall-Ngai MJ, Callaerts P, de Couet HG. Preparation of genomic DNA from Hawaiian bobtail squid (Euprymna scolopes) tissue by cesium chloride gradient centrifugation. Cold Spring Harb Protoc 2009. 2009(11),pdb.prot5319
Lee PN, McFall-Ngai MJ, Callaerts P, de Couet HG. The Hawaiian bobtail squid (Euprymna scolopes): a model to study the molecular basis of eukaryote-prokaryote mutualism and the development and evolution of morphological novelties in cephalopods. Cold Spring Harb Protoc 2009. 2009(11),pdb.emo135
- Handelsman J, McFall-Ngai MJ. Microbial Symbiosis: In Sickness and in Health. DNA and Cell Biology 2009. 28(8),359-60
Troll JV, Adin DM, Wier AM, Paquette N, Silverman N, Goldman WE, Stadermann FJ, Stabb EV, McFall-Ngai MJ. Peptidoglycan induces loss of a nuclear peptidoglycan recognition protein during host tissue development in a beneficial animal-bacterial symbiosis. Cell. Microbiol. 2009. 11(7),1114-27
- Tong D, Rozas NS, Oakley TH, Mitchell J, Colley NJ, McFall-Ngai MJ. Evidence for light perception in a bioluminescent organ. Proc. Natl. Acad. Sci. U.S.A. 2009. 106(24),9836-41
- Adin DM, Engle JT, Goldman WE, McFall-Ngai MJ, Stabb EV. Mutations in ampG and lytic transglycosylase genes affect the net release of peptidoglycan monomers from Vibrio fischeri. J. Bacteriol. 2009. 191(7),2012-22
- Nyholm SV, Stewart JJ, Ruby EG, McFall-Ngai MJ. Recognition between symbiotic Vibrio fischeri and the haemocytes of Euprymna scolopes. Environ. Microbiol. 2009. 11(2),483-93
- Castillo MG, Goodson MS, McFall-Ngai MJ. Identification and molecular characterization of a complement-C3 molecule in a lophotrochozoan, the Hawaiian bobtail squid Eupyrmna scolopes. Dev. Comp. Immunol. 2009. 33(1),69-76
- McFall-Ngai MJ (co-author with other members of the committee). A new biology for the 21st century. 2009. 98
- McFall-Ngai, MJ. Are biologists in 'future shock'? Symbiosis integrates biology across domains. Nat. Rev. Microbiol. 2008. 6(10),789-92
- Chun CK, Troll JV, Koroleva I, Brown B, Manzella L, Snir E, Almabrazi H, Scheetz TE, Bonaldo Mde F, Casavant TL, Soares MB, Ruby EG, McFall-Ngai MJ. Effects of colonization, luminescence, and autoinducer on host transcription during development of the squid-vibrio association. Proc. Natl. Acad. Sci. U.S.A. 2008. 105(32),11323-8
- Adin DM, Phillips NJ, Gibson BW, Apicella MA, Ruby EG, McFall-Ngai MJ, Hall DB, Stabb EV. Characterization of htrB and msbB mutants of the light organ symbiont Vibrio fischeri. Appl. Environ. Microbiol. 2008. 74(3),633-44
- McFall-Ngai MJ. Quick Guide: The Hawaiian Bobtail Squid. Curr. Biol. 2008. 18(22),R1043-R1044
- Dethlefsen L, McFall-Ngai MJ, Relman DA. An ecological and evolutionary perspective on human-microbe mutualism and disease. Nature 2007. 449811-8
- Whistler CA, Koropatnick TA, Pollack A, McFall-Ngai MJ, Ruby EG. The GacA global regulator of Vibrio fischeri is required for normal host tissue responses that limit subsequent bacterial colonization. Cell. Microbiol. 2007. 9(3),766-78
- Koropatnick TA, Kimbell JR, McFall-Ngai MJ. Responses of host hemocytes during the initiation of the squid-Vibrio symbiosis. Biol. Bull. 2007. 212(1),29-39
- McFall-Ngai MJ. Care for the community: A memory-based immune system may have evolved in vertebrates because of the need to recognize and manage complex communities of beneficial microbes. Nature 2007. 445153
- McFall-Ngai MJ. The squid-vibrio association: A naturally occurring experimental model of animal-bacterial partnerships. 2007.
- McFall-Ngai MJ, de Lorenzo V. The ultimate rendezvous: microbial ecology meets industrial microbiology. Curr. Opin. Microbiol. 2007. 10205-6
- McFall-Ngai, MJ. Love the one you're with: vertebrate guts shape their microbiota. Cell 2006. 127(2),247-9
- Cloud-Hansen KA, Peterson SB, Stabb EV, Goldman WE, McFall-Ngai MJ, Handelsman J. Breaching the great wall: peptidoglycan and microbial interactions. Nat. Rev. Microbiol. 2006. 4(9),710-6
- Chun CK, Scheetz TE, Bonaldo Mde F, Brown B, Clemens A, Crookes-Goodson WJ, Crouch K, DeMartini T, Eyestone M, Goodson MS, Janssens B, Kimbell JL, Koropatnick TA, Kucaba T, Smith C, Stewart JJ, Tong D, Troll JV, Webster S, Winhall-Rice J, Yap C, Casavant TL, McFall-Ngai MJ, Soares MB. An annotated cDNA library of juvenile Euprymna scolopes with and without colonization by the symbiont Vibrio fischeri. BMC Genomics 2006. 7154
- Goodson MS, Crookes-Goodson WJ, Kimbell JR, McFall-Ngai MJ. Characterization and role of p53 family members in the symbiont-induced morphogenesis of the Euprymna scolopes light organ. Biol. Bull. 2006. 211(1),7-17
- Kimbell JR, Koropatnick TA, McFall-Ngai MJ. Evidence for the participation of the proteasome in symbiont-induced tissue morphogenesis. Biol. Bull. 2006. 211(1),1-6
- Sycuro LK, Ruby EG, McFall-Ngai MJ. Confocal microscopy of the light organ crypts in juvenile Euprymna scolopes reveals their morphological complexity and dynamic function in symbiosis. J. Morphol. 2006. 267(5),555-68
- McFall-Ngai, MJ, Gordon JI. Experimental models of symbiotic host-microbial relationships: understanding the underpinnings of beneficence and the origins of pathogenesis. 2006.
McFall-Ngai MJ (co-author with other members of the committee). Treating Infectious Diseases in a Microbial World: Report of Two Workshops on Novel Antimicrobial Therapeutics. 2006. 103
- Goodson MS, Kojadinovic M, Troll JV, Scheetz TE, Casavant TL, Soares MB, McFall-Ngai MJ. Identifying components of the NF-kappaB pathway in the beneficial Euprymna scolopes-Vibrio fischeri light organ symbiosis. Appl. Environ. Microbiol. 2005. 71(11),6934-46
- McFall-Ngai MJ, Henderson B, Ruby EG. The Influence of Cooperative Bacteria on Animal Host Biology. 2005.
- Davidson SK, Koropatnick TA, Kossmehl R, Sycuro L, McFall-Ngai MJ. NO means 'yes' in the squid-vibrio symbiosis: nitric oxide (NO) during the initial stages of a beneficial association. Cell. Microbiol. 2004. 6(12),1139-51
Koropatnick TA, Engle JT, Apicella MA, Stabb EV, Goldman WE, McFall-Ngai MJ. Microbial factor-mediated development in a host-bacterial mutualism. Science 2004. 306(5699),1186-8
Nyholm SV, McFall-Ngai MJ. The winnowing: establishing the squid-vibrio symbiosis. Nat. Rev. Microbiol. 2004. 2(8),632-42
- Kimbell JR, McFall-Ngai MJ. Symbiont-induced changes in host actin during the onset of a beneficial animal-bacterial association. Appl. Environ. Microbiol. 2004. 70(3),1434-41
- Ruby EG, Henderson B, McFall-Ngai MJ. We Get By with a Little Help from Our (Little) Friends. Science 2004. 303(5662),1305-7
- Crookes WJ, Ding LL, Huang QL, Kimbell JR, Horwitz J, McFall-Ngai MJ. Reflectins: the unusual proteins of squid reflective tissues. Science 2004. 303(5655),235-8
- Nyholm SV, McFall-Ngai MJ. Dominance of Vibrio fischeri in secreted mucus outside the light organ of Euprymna scolopes: the first site of symbiont specificity. Appl. Environ. Microbiol. 2003. 69(7),3932-7
- Kimbell JR, McFall-Ngai MJ. The squid-Vibrio symbioses: from demes to genes. Integr. Comp. Biol. 2003. 43(2),254-60
- Nyholm SV, Deplancke B, Gaskins HR, Apicella MA, McFall-Ngai MJ. Roles of Vibrio fischeri and nonsymbiotic bacteria in the dynamics of mucus secretion during symbiont colonization of the Euprymna scolopes light organ. Appl. Environ. Microbiol. 2002. 68(10),5113-22
McFall-Ngai MJ. Unseen forces: the influence of bacteria on animal development. Dev. Biol. 2002. 242(1),1-14
- Kimbell JR, McFall-Ngai MJ, Roderick GK. Two genetically distinct populations of bobtail squid, Euprymna scolopes, exist on the island of Oahu. Pac. Sci. 2002. 56(3),347-55
- Foster JS, von Boletzky S, McFall-Ngai MJ. A Comparison of the Light Organ Development of Sepiola robusta naef and Euprymna scolopes berry (CEPHALOPODA: SEPIOLIDAE). Bull. Marine Science 2002. 70(1),141-53
- McFall-Ngai MJ. Identifying 'prime suspects': symbioses and the evolution of multicellularity. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 2001. 129(4),711-23
- Stabb EV, Visick DS, Millikan AA, Corcoran L, Gilson SV, Nyholm MJ, McFall-Ngai MJ, Ruby EG. The Vibrio fischeri-Euprymna scolopes symbiosis: A model marine animal-bacteria interaction. 2001. 269-77
McFall-Ngai MJ, Ruby EG. Developmental biology in marine invertebrate symbioses. Curr. Opin. Microbiol. 2000. 3(6),603-7
Foster JS, Apicella MA, McFall-Ngai MJ. Vibrio fischeri lipopolysaccharide induces developmental apoptosis, but not complete morphogenesis, of the Euprymna scolopes symbiotic light organ. Dev. Biol. 2000. 226(2),242-54
- Doino Lemus J, McFall-Ngai MJ. Alterations in the proteome of the Euprymna scolopes light organ in response to symbiotic Vibrio fischeri. Appl. Environ. Microbiol. 2000. 66(9),4091-7
Nyholm SV, Stabb EV, Ruby EG, McFall-Ngai MJ. Establishment of an animal-bacterial association: recruiting symbiotic vibrios from the environment. Proc. Natl. Acad. Sci. U.S.A. 2000. 97(18),10231-5
- McFall-Ngai MJ. Negotiations between animals and bacteria: the 'diplomacy' of the squid-vibrio symbiosis. Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. 2000. 126(4),471-80
- Visick KL, Foster J, Doino J, McFall-Ngai MJ, Ruby EG. Vibrio fischeri lux genes play an important role in colonization and development of the host light organ. J. Bacteriol. 2000. 182(16),4578-86
- Hirsch AM, McFall-Ngai MJ. Fundamental Concepts in Symbiotic Interactions: Light and Dark, Day and Night, Squid and Legume. J. Plant Growth Regul. 2000. 19(2),113-130
Visick KL, McFall-Ngai MJ. An exclusive contract: specificity in the Vibrio fischeri-Euprymna scolopes partnership. J. Bacteriol. 2000. 182(7),1779-87
Ruby EG, McFall-Ngai MJ. Oxygen-utilizing reactions and symbiotic colonization of the squid light organ by Vibrio fischeri. Trends Microbiol. 1999. 7(10),414-20
- Small AL, McFall-Ngai MJ. Halide peroxidase in tissues that interact with bacteria in the host squid Euprymna scolopes. J. Cell. Biochem. 1999. 72(4),445-57
- McFall-Ngai MJ. Consequences of evolving with bacterial symbionts: Insights from the Squid-Vibrio associations. Annu. Rev. Ecol. Syst. 1999. 30235-56
McFall-Ngai, M. J. The Development of Cooperative Associations Between Animals and Bacteria: Establishing Detente Among Domains. American Zoologist 1998. 38(4),593-608
- Montgomery MK, McFall-Ngai MJ. Late postembryonic development of the symbiotic light organ of Euprymna scolopes (Cephalopoda: Sepiolidae). Biol. Bull. 1998. 195(3),326-36
Nyholm SV, McFall-Ngai MJ. Sampling the light-organ microenvironment of Euprymna scolopes: description of a population of host cells in association with the bacterial symbiont Vibrio fischeri. Biol. Bull. 1998. 195(2),89-97
- Nishiguchi MK, Ruby EG, McFall-Ngai MJ. Competitive dominance among strains of luminous bacteria provides an unusual form of evidence for parallel evolution in Sepiolid squid-vibrio symbioses. Appl. Environ. Microbiol. 1998. 64(9),3209-13
Foster JS, McFall-Ngai MJ. Induction of apoptosis by cooperative bacteria in the morphogenesis of host epithelial tissues. Dev. Genes Evol. 1998. 208(6),295-303
- Lamarcq LH, McFall-Ngai MJ. Induction of a gradual, reversible morphogenesis of its host's epithelial brush border by Vibrio fischeri. Infect. Immun. 1998. 66(2),777-85
- McFall-Ngai MJ, Brennan C, Weis V, Lamarcq L. Mannose adhesin-glycan interactions in the Euprymna scolopes-Vibrio fischeri symbiosis. 1998. 273-6
- Nishiguchi MK, Ruby EG, McFall-Ngai MJ. Phenotypic bioluminescence as an indicator of competitive dominance in the Euprymna-Vibrio symbiosis. 1998. 123-6
- Nyholm SV, McFall-Ngai MJ. Sampling the light-organ microenvironment of Euprymna scolopes: description of a population of host cells in association with the bacterial symbiont Vibrio fischeri. Biol. Bull. 1998. 195(2),89-97
- McFall-Ngai, MJ. Pioneering the Squid-Vibrio Model. ASM News 1998. 64(11),639-45
McFall-Ngai MJ, Ruby EG. Sepiolids and Vibrios: When First They Meet. BioScience 1998. 48(4),257-65
- McFall-Ngai MJ. Dragonfly 1997.
- Holland LZ, McFall-Ngai MJ, Somero GN. Evolution of lactate dehydrogenase-A homologs of barracuda fishes (Genus Sphyraena) from different thermal environments: Differences in kinetic properties and thermal stability are due to amino acid substitutions outside of the active site. Biochemistry 1997. 36(11),3207-15
- Nishiguchi MK, Ruby EG, McFall-Ngai MJ. Phenotypic bioluminescence as an indicator of competitive dominance in the Euprymna-Vibrio symbiosis. 1997. 123-26
- Weis VM, Small AL, McFall-Ngai MJ. A peroxidase related to the mammalian antimicrobial protein myeloperoxidase in the Euprymna-Vibrio mutualism. Proc. Natl. Acad. Sci. U.S.A. 1996. 93(24),13683-8
- McFall-Ngai MJ. Science Spectrum 1996. 4
- Boettcher KJ, Ruby EG, McFall-Ngai MJ. Bioluminescence in the symbiotic squid Euprymna scolopes is controlled by a daily biological rhythm. J. Comp. Physiol. 1996. 17965-73
- Doino JA, McFall-Ngai MJ. A Transient Exposure to Symbiosis-Competent Bacteria Induces Light Organ Morphogenesis in the Host Squid. Biol. Bull. 1995. 189(3),347-55
- Gates RD, Hoegh-Guldberg O, McFall-Ngai MJ, Bil KY, Muscatine L. Free amino acids exhibit anthozoan "host factor" activity: they induce the release of photosynthate from symbiotic dinoflagellates in vitro. Proc. Natl. Acad. Sci. U.S.A. 1995. 92(16),7430-4
- Montgomery MK, McFall-Ngai MJ. The inductive role of bacterial symbionts in the morphogenesis of a squid light organ. Amer. Zool. 1995. 35372-380
- McFall-Ngai MJ. Animal-bacterial interactions in the early life history of marine invertebrates: The Euprymna scolopes/Vibrio fischeri symbiosis Amer. Zool. 1994. 34554-61
- Montgomery MK, McFall-Ngai MJ. Bacterial symbionts induce host organ morphogenesis during early postembryonic development of the squid Euprymna scolopes. Development 1994. 120(7),1719-29
- Tomarev SI, Zinovieva RD, Weis VM, Chepelinsky AB, Piatigorsky J, McFall-Ngai MJ. Abundant mRNAs in the squid light organ encode proteins with a high similarity to mammalian peroxidases. Gene 1993. 132(2),219-26
- Montgomery MJ, McFall-Ngai MJ. Embryonic development of the light organ of the sepiolid squid Euprymna scolopes Berry. Biol. Bull. 1993. 184(3),296-308
- Weis VM, Montgomery MK, McFall-Ngai MJ. Enhanced production of ALDH-like protein in the bacterial light organ of the sepiolid squid Euprymna scolopes. Biol. Bull. 1993. 184(3),309-321
- Dove S, Horwitz J, McFall-Ngai MJ. A biochemical characterization of the photophore lenses of the midshipman fish. J. Comp. Physiol. 1993. 172565-72
- Small AL, McFall-Ngai MJ. Changes in the oxygen environment of a symbiotic squid light organ in response to infection by its luminous bacterial symbiont. Amer. Zool. 1993. 3361A
- Montgomery MK, McFall-Ngai MJ. The muscle-derived lens of a squid bioluminescent organ is biochemically convergent with the ocular lens. Evidence for recruitment of aldehyde dehydrogenase as a predominant structural protein. J. Biol. Chem. 1992. 267(29),20999-1003
- Ruby EG, McFall-Ngai MJ. A squid that glows in the night: development of an animal-bacterial mutualism. J. Bacteriol. 1992. 174(15),4865-70
- Hensey S, McFall-Ngai MJ. A surface peptide of the bacterium Vibrio fischeri plays a key role in specificity and recognition in the symbiosis with the squid Euprymna scolopes. Amer. Zool. 1992. 3232A
McFall-Ngai MJ, Ruby EG. Symbiont recognition and subsequent morphogenesis as early events in an animal-bacterial mutualism. Science 1991. 254(5037),1491-4
- Yu N, Cai M, Lee B, Kuck J, McFall-Ngai MJ, Horwitz J. Resonance Raman detection of a carotenoid in the lens of the deep-sea hatchetfish. Exp. Eye Res. 1991. 52475-9
- McFall-Ngai MJ, Toller W. Frontiers in the study of the biochemistry and molecular biology of vision and luminescence in fishes. 1991. 77-107
- McFall-Ngai MJ. Luminous bacterial symbioses in fish evolution: adaptive radiation among the leiognathid fishes. 1991. 381-409
- McFall-Ngai MJ, Morin JG. Camouflage by disruptive illumination in leiognathids, a family of shallow-water, bioluminescent fishes. J. Exp. Biol. 1991. 156119-37
- McFall-Ngai MJ, Montgomery MK. The anatomy and morphology of the adult bacterial light organ of Euprymna scolopes Berry (Cephalopoda: Sepiolidae). Biol. Bull. 1990. 179(3),332-9
- McFall-Ngai MJ, Horwitz J. A comparative study of the thermal stability of the vertebrate eye lens: Antarctic ice fish to the desert iguana. Exp. Eye Res. 1990. 50(6),703-9
- Ruby EG, McFall-Ngai MJ. Morphological and physiological differentiation in the luminous bacterial symbionts of Euprymna scolopes. 1990. 323-6
- McFall-Ngai MJ. Crypsis in the pelagic environment. Amer. Zool. 1990. 30175-88
- McFall-Ngai MJ, Ruby EG. The changing host-tissue/symbiont relationship in the developing light organ of Euprymna scolopes (Cephalopoda: Sepiolidae). 1990.
- McFall-Ngai MJ, Ding LL, Horwitz J. Comparative biochemistry of lens pigmentation in mesopelagic fishes. Biol. Bull. 1988. 175(3),397-402
- Dunlap PV, McFall-Ngai MJ. Initiation and control of the bioluminescent symbiosis between Photobacterium leiognathi and leiognathid fish. Ann. N. Y. Acad. Sci. 1987. 503269-83
- McFall-Ngai MJ, Horwitz J, Ding LL, Lacey L. Age-dependent changes in the heat-stable crystallin, beta basic-principle, of the human lens. Curr. Eye Res. 1986. 5387-94
- McFall-Ngai MJ, Crescitelli F, Childress J, Horwitz J. Patterns of pigmentation in the eye lens of the deep-sea hatchet-fish, Argyropelecus affinis Garman. J. Comp. Physiol. 1986. 159791-800
- McFall-Ngai MJ, Ding LL, Takemoto LJ, Horwitz J. Spatial and temporal mapping of the age-related changes in human lens crystallins. Exp. Eye Res. 1985. 41(6),745-58
- McFall-Ngai MJ, Ding LL, Horwitz J. Biochemical aging of human soluble lens proteins. Exp. Eye Res. 1985. 41745-58
- Crescitelli F, McFall-Ngai MJ, Horwitz J. The photic adaptation hypothesis: support from organisms from different habitats. J. Comp. Physiol. 1985. 157323-33
- Horwitz J, McFall-Ngai MJ, Ding LL, Yaron O. Thermal stability of lens crystallins. 1985. 227-40
- Peterson JA, Benson JA, Morin JG, McFall-Ngai MJ. Scaling in tensile skeletons: scale dependent length dimensions of the mammalian Achilles tendon. J. Zool. Lond. 1984. 202361-72
- McFall-Ngai MJ, Dunlap PV. External and internal sexual dimorphism in leiognathid fishes:morphological evidence for sex-specific bioluminescent signalling. J. Morph. 1984. 18271-83
- Dunlap PV, McFall-Ngai MJ. Leiognathus elongatus (Perciformes:Leiognathidae): Two distinct species based on morphological and anatomical characters. Copeia 1984. 4884-92
- McFall-Ngai MJ, Dunlap PV. Three new modes of luminescence in the leiognathid fish, Gazza minuta. Mar. Biol. 1983. 74227-37
- McFall-Ngai MJ. Adaptations for reflection of bioluminescent light in the gas bladders of Leiognathus equulus (Perciformes:Leiognathidae). J. Exp. Zool. 1983. 22723-33
- Peterson JA, Benson JA, McFall-Ngai MJ, Morin J, Ow C. Scaling in tensile skeletons: Structures with scale-independent length dimensions. Science 1982. 2171267-70
- McFall-Ngai MJ. Giving microbes their due-animal life in a microbially dominant world. J Exp Biol 2015. 218(12),1968-1973
- McFall-Ngai MJ. Out of sight, out of mind. Environ Microbiol Rep 2015. 7(1),29-30
- Krasity BC, Troll JV, Lehnert EM, Hackett KT, Dillard JP, Apicella MA, Goldman WE, Weiss JP, McFall-Ngai MJ. Structural and functional features of a developmentally regulated lipopolysaccharide-binding protein. mBio 2015. 6(5), e01193-15
- Aschtgen M-S, Wetzel K, Goldman W, McFall-Ngai MJ and Ruby EG. Vibrio fischeri-derived outer membrane vesicles trigger host development. Cellul Microbiol 2015. 18(4),488-499